Mashpit is a portable genome-search tool that runs on a Raspberry Pi, enabling rapid, offline screening of Salmonella genomes. Using MinHash sketches, it scans hundreds of thousands of genomes in seconds, offering small or low-resource labs a fast, accessible way to identify related isolates before performing high-resolution follow-up analyses.

My research tackles PFAS (polyfluoroalkyl substances) or “forever chemicals,” found in everyday products and linked to serious health risks. Blood testing shows 95% contamination rates. The project identifies specialised bacteria capable of breaking PFAS down nearly completely within days, offering a promising biological solution to reduce environmental and human exposure to these persistent toxic chemicals.

This research searches for new antibiotics in deep-sea sponge bacteria that have evolved for 580 million years to defend their hosts. By growing these never-before-seen microbes and testing them against superbugs like MRSA, the project aims to discover urgently needed antibiotics to combat rising antimicrobial resistance.