mGlu5 Modulation Reduces Alcohol Self-Administration in an Animal Model of THC and Alcohol Co-Use - Bailey Adams

Year
2024
Summary

This research examines how combined THC and alcohol use alters neural communication and increases alcohol consumption. Using animal models, the study shows that co-use disrupts the glutamate system, heightening motivation to drink. Regulating glutamate with the compound CDPPB reduces alcohol intake, highlighting glutamate as a promising therapeutic target for addictio