Mapping Protein Networks: A Path to Genetic Disease Therapies - Fatima Lukmani

Year
2025
Tags
PKD
polycystic kidney disease
protein interactions
genetic mutations
BioID
mass spectrometry
kidney function
personalised medicine
molecular networks
biomedical research
targeted therapies
TMU
Summary

The speaker studies polycystic kidney disease by identifying missing or damaged proteins that destabilize the kidney’s filtration network. Using BioID and mass spectrometry, they map healthy versus diseased protein interactions to pinpoint weak spots. This work aims to enable targeted therapies and personalised treatments for PKD patients.