How Tissue Stiffness Talks to Cells During Wound Healing. Understanding Autophagy in Fibroblasts - Mahboubeh Kavoosi

Healing depends on a balance between extracellular matrix stiffness and cellular recycling through autophagy. This research shows that disrupted balance leads to chronic wounds or fibrotic scarring. By engineering materials with tunable stiffness, the work reveals how cells “sense” their environment, opening new paths to guide healthier wound healing.