Slowing Down Sperm with Non-Hormonal Male Contraceptive Agents - Srujana Mohanty

Year
2025
Organisation
University of Minnesota
Tags
male contraception
non-hormonal contraceptive
reproductive health
fertility research
fertility
Catsper
SLO3
sperm motility
drug discovery
medicinal chemistry
family planning
reproductive biology
contraceptive innovation
Minnesota
Summary

This research develops a non-hormonal male contraceptive by blocking two sperm proteins, Catsper and SLO3, that enable hyperactivated “power swimming” required for fertilization. By designing molecules that inhibit these proteins, the project aims to create a safe, reversible contraceptive option that avoids hormonal side effects.