This research develops nanoscale robots made from synthetic DNA capable of navigating and manipulating molecular environments. Using programmable DNA interactions and thermodynamic processes, the work focuses on maze-solving behaviors as a foundation for future applications including allergen removal, nanomaterial assembly, tissue engineering, and programmable molecular systems operating in the physical world.

This research investigates the century-old Invar effect in iron–palladium alloys under extreme pressure. Using synchrotron experiments and thermodynamic analysis, the study shows that magnetic entropy and vibrational entropy precisely counterbalance each other, eliminating thermal expansion. The findings reveal strong spin-phonon coupling as a key mechanism underlying pressure-induced Invar behavior.