The Road to the Heart for Gene Therapy - Lauren Switala

Year
2025
Tags
genetic cardiomyopathy
heart disease
gene therapy
targeted drug delivery
chemokines
immune evasion
cardiovascular research
precision medicine
pediatric heart disease
translational medicine
Case Western
Summary

Genetic cardiomyopathies arise from DNA errors that disrupt vital heart proteins and can be fatal in childhood. This research improves heart-targeted gene therapy by guiding treatments through the bloodstream using chemokine “traffic signals” and avoiding immune interference, enabling therapies to reach the heart more efficiently and potentially cure inherited heart disease.