This research develops self-sterilising polymer coatings that become highly acidic when exposed to moisture, rapidly destroying harmful bacteria such as MRSA and E. coli. Designed for hospitals, classrooms, and other high-contact surfaces, these materials could reduce infections without harsh chemicals, helping prevent the spread of antibiotic-resistant bacteria.

This thesis developed multifunctional 3D-printed scaffolds for repairing critical-size mandibular bone defects. Using bioactive ceramics, surface coatings, and prevascularization strategies, it promoted both osteogenesis and angiogenesis. Results show that combining geometry, materials, and biological signals enables synergistic tissue regeneration, offering less-invasive alternatives to autologous bone grafts.