This research develops orally administered nanoparticles that target the lymphatic system to treat lupus and osteoporosis simultaneously. By delivering drugs directly to affected tissues while avoiding the bloodstream, the approach reduces toxicity, suppresses inflammatory and bone-damaging genes, and offers a more effective strategy for treating these complex chronic diseases.

This research investigates how Type 1 diabetes affects bone development during childhood and adolescence. Using high-resolution bone imaging and blood glucose data, the study explores whether blood sugar levels, variability, and disease duration influence bone health. Early findings suggest that diagnosis closer to puberty may be associated with lower bone density.

Obesity and type 2 diabetes weaken bones, increasing fracture risk. This research uses animal models of lean, obese, and diabetic conditions to examine how these diseases affect bone strength. By identifying the mechanisms behind bone fragility, the study aims to guide future dietary and therapeutic strategies to protect bone health in affected populations.