A biomedical engineering team developed a handheld device that measures newborn heart rate in under 10 seconds—far faster than current tools. Using a novel sensor and real-time algorithms, it improves clinicians’ ability to intervene within the critical first minute after birth. Clinical trials are complete, the device is patented, and commercialization is underway.
The speaker investigates why surgical sutures often fail and explores bio-inspired alternatives. Studying freshwater mussels—experts at sticking to wet surfaces—they analyze adhesive proteins to design stronger, water-compatible tissue adhesives. This research aims to create safer, more reliable surgical closure methods that reduce complications, infections, and reliance on traditional suturing.
Prion diseases like CJD are extremely hard to detect early because harmful prions resemble normal brain proteins. This research introduces a new “flashbody” detection tool that binds only disease-causing prions, providing rapid, accurate, equipment-free diagnosis. Early lab results and patient-screening trials are promising, with potential applications to Alzheimer’s and other dementias.
This research develops one of the most advanced human-engineered brain models to better study Alzheimer’s disease and test treatments. Using microfluidic chips containing all key brain cell types, blood-vessel systems, and Alzheimer’s-model neurons, the project enables efficient drug testing, personalised disease modelling, and the possibility of replacing animal testing in the search for a cure.
Type 1 diabetes destroys insulin-producing cells, leaving patients dependent on lifelong injections. Islet transplants could provide freedom, but most cells die quickly. This research uses drug-loaded microparticles that protect transplanted islets, boosting survival, insulin production, and diabetes reversal. The approach could cut costs, reduce donor needs, and transform treatment for multiple diseases.
This research aims to solve the major weakness of mRNA vaccines—the need for constant cold storage—by packaging them inside ultra-stable protein “boxes” called encapsulins. These naturally robust containers protect mRNA in extreme environments. A working prototype now exists, offering the potential for globally distributable, freezer-free vaccines that remain effective anywhere.
Presbyopia, the age-related loss of near vision, occurs when the eye’s crystalline lens stiffens. A known lens-softening drug, Bistatin, affects too many eye structures to be safe. This research creates a targeted antibody–drug conjugate that delivers Bistatin only to the lens, restoring flexibility and offering a potential non-surgical treatment.
Brain surgeons struggle to distinguish tumor from healthy tissue in real time, risking life-altering surgical mistakes. This research uses polarimetric imaging and machine-learning algorithms to reveal tumor borders instantly by analysing subtle differences in tissue structure. Faster, clearer, real-time imaging could revolutionise brain surgery and dramatically improve patient outcomes.
My research presents a self-administered microneedle patch made from hyaluronic acid that delivers vaccines quickly, painlessly, and effectively. Testing with a COVID-19 spike RBD antigen shows immune responses comparable to traditional injections. The patches are low-risk, easy to use, and can be stored at room temperature for a month—ideal for widespread vaccination.