This research investigates how coordinated and random patterns of cell division shape facial development. Using 3D imaging of mouse embryos, it reveals that the direction of cell division—not just its location—drives tissue growth. Balancing orderly and chaotic cellular behaviours may be key to understanding healthy face formation and preventing developmental defects.
Congenital heart defects are the leading cause of infant death from birth defects. This research develops a high-throughput method to test genetic mutations in key heart genes like TBX5, identifying which variants disrupt heart development. The approach improves diagnosis, informs gene therapy, and advances understanding of why hearts fail before birth.