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Building Better Bionics: PhD Thesis Defense - Tony Shu

bionics
prosthetics
transfemoral amputation
powered knee prosthesis
rehabilitation engineering
human-in-the-loop control
neuromechanics
neuromuscular interface
agonist-antagonist myoneural interface
AMI
phantom proprioception
mechanoreceptors
muscle spindles
Golgi tendon organs
afferent feedback
efferent control
EMG control
intramuscular electrodes
signal-to-noise ratio
impact artifacts
socket limitations
titanium implant
bone-anchored prosthesis
osteoperception
OMP
osseointegrated mechanoneural prosthesis
series elastic actuation
impedance control
torque modulation
stiffness and damping
finite-state machine
gait phase detection
load cells
ultrasound measurement
fMRI motor cortex activation
motor intent decoding
virtual joint control
obstacle drills
agility metrics
K3/K4 mobility levels
embodiment
assistive robotics
bio-mechatronics co-design
MIT

This defense argues prostheses must exchange information, not just energy, with the nervous system. It combines soft-tissue AMI revision, osseointegration with implanted electrodes (OMP), and impedance control to enable continuous powered-knee modulation. Pilot studies show improved neuromechanics, cortical activation, cleaner EMG, better task performance, and greater embodiment versus socket-based approaches.

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