My research presents a self-administered microneedle patch made from hyaluronic acid that delivers vaccines quickly, painlessly, and effectively. Testing with a COVID-19 spike RBD antigen shows immune responses comparable to traditional injections. The patches are low-risk, easy to use, and can be stored at room temperature for a month—ideal for widespread vaccination.

This research uses harmless insect-specific viruses to block mosquitoes from becoming infected with dangerous human viruses like dengue or Zika. Through superinfection exclusion, an already-infected mosquito can’t host a second virus. The work explores releasing “pre-infected” mosquitoes as a safe, sustainable method to prevent disease transmission globally.