This research investigates episodic ataxia type 1, a rare disorder causing sudden loss of coordination. A genetic mutation triggers abnormal brain firing and electrical waves in the cerebellum. By tracking these waves in mice, the work aims to identify ways to prevent attacks and restore motor control.

Migraine affects over 10% of people and disproportionately impacts women. This research studies sex differences in brain circuits using mouse models to understand why. By manipulating neural pathways, findings show certain circuits trigger migraine-like sensitivity only in females. Mapping these circuits may enable personalized, more effective migraine treatments.