This research investigates episodic ataxia type 1, a rare disorder causing sudden loss of coordination. A genetic mutation triggers abnormal brain firing and electrical waves in the cerebellum. By tracking these waves in mice, the work aims to identify ways to prevent attacks and restore motor control.

Epilepsy affects millions worldwide and can limit everyday activities. Some forms arise from genetic mutations in GABAA_AA​ receptors, disrupting the balance between brain excitation and inhibition. This research examines how these mutations reduce receptor levels and explores drug strategies to restore inhibition, paving the way for improved epilepsy treatments.

This research develops a novel MRI-based method to detect blood–brain barrier leakage associated with stroke. By comparing pre- and post-contrast brain images, the approach enables early detection, monitoring of treatment response, and risk prediction, offering new possibilities for stroke prevention and improved patient outcomes

This research inserts a human-specific DNA sequence into mice to study cerebral cortex development. The modified mice show increased upper-layer neurons and glial cells, revealing how human brain evolution supports higher cognition. These findings improve understanding of human brain specialization and the origins of neurological disorders.