My research investigates AU403, a novel LXR agonist, as a potential treatment for frontotemporal dementia. Using mouse brain slice models, the study shows that AU403 restores damaged myelin, improves neuronal communication, and reverses disease-like symptoms, offering hope for a condition with no approved therapies.

This research investigates whether heat acclimation affects cold tolerance in soldiers. Participants undergo controlled cold exposure before and after intensive heat training. By measuring temperature regulation, sweating, and dexterity, the study aims to guide military deployment decisions and ensure soldiers can perform confidently across extreme environments.

This research examines how real-world microplastics and nanoplastics affect human brain immune cells. Using plastics from everyday consumer items, it shows rapid cellular stress and mitochondrial damage linked to neurodegenerative disease. The findings suggest current laboratory studies may underestimate the true health risks of chronic plastic exposure.