This research explores how the hippocampus and prefrontal cortex communicate to support memory for sequences of events. By understanding how these brain regions track past, present, and future, the work aims to shed light on cognitive impairments seen in disorders such as Alzheimer’s disease and depression.

This research investigates why women are more vulnerable to stress-related disorders. Using a mouse model of acute trauma, the study shows that estrogen levels in the hippocampus drive memory disruption after stress. Blocking local estrogen production protects memory, revealing sex-specific mechanisms relevant for targeted treatments.

This talk describes research on how the brain learns and remembers by recording neural activity in mice navigating virtual environments. By studying hippocampal and cortical neurons, the work reveals how the brain builds cognitive maps of space and experience, offering insights into memory loss and Alzheimer’s disease.