This research develops an affordable, rapid genetic testing system to personalize antidepressant treatment. By detecting DNA mutations that affect drug metabolism, the technology helps doctors prescribe the right medication for each patient. The goal is to reduce ineffective treatments and improve mental health care—especially for veterans struggling with PTSD and depression.
This research investigates why women are more vulnerable to stress-related disorders. Using a mouse model of acute trauma, the study shows that estrogen levels in the hippocampus drive memory disruption after stress. Blocking local estrogen production protects memory, revealing sex-specific mechanisms relevant for targeted treatments.
2018
This research investigates why people struggle with interpersonal problem-solving, especially in the context of psychological disorders. Using surveys and the MEPS task with 160 participants, the study found that emotion-regulation difficulties and experiential avoidance explain 46% of poor problem-solving. Improving emotional acceptance may significantly enhance responses to interpersonal conflict.