This research develops a rapid, light-based method to study viral fusion, the first step of infection. By applying split NanoLuc technology to HIV, it reveals strain-specific fusion behaviors and unexpected regulatory steps, providing tools that can accelerate responses to future pandemics such as COVID-19.
A $2 portable HIV test chip that combines PCR-level sensitivity with home-test simplicity. Using magnetic microparticles, custom probes, and automated processing, it delivers rapid color-change results from a single drop of blood. The system could diagnose HIV and other viruses quickly, affordably, and anywhere.
Chronic diseases exhaust the body’s CD8 T cells, weakening their ability to fight infections and cancer. This research identifies CD7 as a key driver of T-cell exhaustion. Removing CD7 keeps T cells active, boosts cytokine production, and improves control of tumors and viruses—offering a promising new immunotherapy target.