This research uses a high-throughput screening platform called EpiScan to identify HIV peptides that bind strongly to MHC molecules and appear on infected cell surfaces. By discovering these immune-visible targets, the work aims to improve detection and elimination of hidden HIV reservoirs, supporting the development of future HIV therapies.

This thesis examines the Soviet AIDS epidemic as a social and political crisis rather than solely a medical one. Through newspapers, diaries, and government documents, the research reveals how AIDS contributed to growing public distrust in Soviet institutions and became part of the broader crises preceding the collapse of the Soviet Union.

This research develops a rapid, accessible technique for analyzing extracellular vesicles (EVs), tiny cellular messengers found in blood. By measuring both the size and molecular contents of individual EVs, the method could enable earlier and more accurate diagnosis of diseases such as cancer, Alzheimer’s, and HIV using simple blood samples.

This research develops a rapid, light-based method to study viral fusion, the first step of infection. By applying split NanoLuc technology to HIV, it reveals strain-specific fusion behaviors and unexpected regulatory steps, providing tools that can accelerate responses to future pandemics such as COVID-19.

A $2 portable HIV test chip that combines PCR-level sensitivity with home-test simplicity. Using magnetic microparticles, custom probes, and automated processing, it delivers rapid color-change results from a single drop of blood. The system could diagnose HIV and other viruses quickly, affordably, and anywhere.

Chronic diseases exhaust the body’s CD8 T cells, weakening their ability to fight infections and cancer. This research identifies CD7 as a key driver of T-cell exhaustion. Removing CD7 keeps T cells active, boosts cytokine production, and improves control of tumors and viruses—offering a promising new immunotherapy target.