This study investigates how immune cells influence Alzheimer’s disease. Using a mouse model, researchers found that removing T cells did not alter amyloid plaque levels but changed microglial behavior, leading to better protection of myelin. The findings suggest T cells may worsen neurodegeneration and highlight new therapeutic possibilities.
Epilepsy affects millions worldwide and can limit everyday activities. Some forms arise from genetic mutations in GABAA_AA receptors, disrupting the balance between brain excitation and inhibition. This research examines how these mutations reduce receptor levels and explores drug strategies to restore inhibition, paving the way for improved epilepsy treatments.
A researcher explains how anatomical differences in the vagus nerve drive inconsistent outcomes in epilepsy treatment. By dissecting and 3D-mapping human vagus nerves, the team reveals major left–right differences, enabling more precise electrode placement. This work promises safer, more effective nerve stimulation therapies for epilepsy and other diseases.