Epilepsy affects millions worldwide and can limit everyday activities. Some forms arise from genetic mutations in GABAA_AA receptors, disrupting the balance between brain excitation and inhibition. This research examines how these mutations reduce receptor levels and explores drug strategies to restore inhibition, paving the way for improved epilepsy treatments.
Gray mold in strawberries is increasingly resistant to fungicides due to genetic mutations. This research identifies resistance levels by testing pathogen samples in the lab, allowing growers to choose effective treatments. Ongoing work analyzes resistance trends and integrates DNA tools to optimize spray programs and reduce waste, ensuring healthier harvests.
The speaker studies polycystic kidney disease by identifying missing or damaged proteins that destabilize the kidney’s filtration network. Using BioID and mass spectrometry, they map healthy versus diseased protein interactions to pinpoint weak spots. This work aims to enable targeted therapies and personalised treatments for PKD patients.