This research uses cavefish to reveal how evolution reshapes the brain. By comparing surface and cave-adapted forms, it shows that neural circuits lost to vision are repurposed for touch and smell. These findings demonstrate how evolution refines existing brain structures to meet environmental demands.
Corneal scarring causes widespread vision loss and is poorly treated by transplantation alone. This research develops a bioengineered corneal glue that both seals and heals wounds by promoting cell infiltration and reducing fibrosis. The approach enables scar-free healing, lowers transplant rejection risk, and offers a regenerative alternative to sutures and conventional sealants.
2016
Presbyopia, the age-related loss of near vision, occurs when the eye’s crystalline lens stiffens. A known lens-softening drug, Bistatin, affects too many eye structures to be safe. This research creates a targeted antibody–drug conjugate that delivers Bistatin only to the lens, restoring flexibility and offering a potential non-surgical treatment.