This anthropological research investigates traditional medicinal uses of psilocybin mushrooms in Lesotho. Interviews with local healers revealed treatment practices that differ substantially from Western clinical models, including low-dose administration over extended periods and applications for epilepsy and psychosis. The findings may broaden future directions for psychedelic medicine research.

This research develops automated tools to identify psychedelic-inspired compounds that restore lost neural connections associated with depression, anxiety, and addiction. Using advanced imaging and custom analysis software, the project screens potential therapeutics that promote neuronal growth, aiming to create treatments that repair brain circuitry rather than simply managing symptoms.

This research investigates whether zinc plays a critical role in the ability of psychedelic drugs to reopen social reward critical periods in the brain. Using mouse models, the study examines how zinc influences social behavior following psychedelic treatment, potentially revealing mechanisms of brain plasticity relevant to autism, social anxiety, and social connection.

Mental health disorders disrupt neural connections in the brain, yet most treatments only manage symptoms. This research explores psychedelic-inspired drugs that restore lost brain connections without hallucinogenic effects, using automated imaging tools to identify compounds that rebuild neural structure and offer lasting recovery.

This research tests whether psychedelics improve adaptability in mice. After learning reward rules, mice with a single psychedelic treatment relearned new rules faster and used more information—learning not only from rewards but also from missed rewards. The findings suggest psychedelics enhance behavioral flexibility, offering clues for developing future mental health treatments.