This research investigates how glioblastoma brain cancer cells invade healthy brain tissue. Using patient-derived tumor organoids and traction force microscopy, the study measures how cancer cells generate and apply forces to move through the brain. Understanding these invasion mechanisms could help develop therapies that slow tumor spread and improve patient survival.
2026
This research investigates how melanoma switches between two gene states—one fast-growing and treatable, the other slow but highly invasive and responsible for brain metastases. By identifying genes that control this transition, the study aims to force melanoma into a more treatable form, improving therapeutic options and patient outcomes.
2025
This research examines how macrophages shift between tumor-fighting and tumor-supporting roles in breast cancer. By identifying signals in the tumor microenvironment and engineering molecular cues to promote tumor-destroying behavior, the work aims to reprogram immune responses and improve therapeutic outcomes for breast cancer patients.