This research explores an injectable, thermosensitive hydrogel to deliver plant-based anticancer drugs for cervical cancer. By stabilizing phytochemicals and enabling localized, controlled release, the hydrogel significantly improves tumor cell killing while reducing side effects, offering a more patient-centered and effective treatment strategy.

Cancer cells survive extreme oxidative stress by importing lipoproteins that deliver vitamin E, a powerful antioxidant. This creates a fire-resistant shield that prevents ferroptotic cell death. Blocking vitamin E delivery or lipoprotein uptake removes this protection, revealing a new vulnerability that could influence tumor growth and treatment response.

This research examines how macrophages shift between tumor-fighting and tumor-supporting roles in breast cancer. By identifying signals in the tumor microenvironment and engineering molecular cues to promote tumor-destroying behavior, the work aims to reprogram immune responses and improve therapeutic outcomes for breast cancer patients.

The speaker develops RADARS, a programmable RNA-guided gene-delivery system that activates only in cells with specific RNA “fingerprints.” Their thesis tackles weak activation when target RNA is rare, creating new mechanisms to bind targets more tightly. These innovations aim to enable safer, cell-specific cancer therapies through precise molecular control.

My research investigates tiny particles released by metastatic cancer cells—messengers that help cancer hide from the immune system. By capturing and analysing these particles, the study aims to uncover how they evade detection and to develop new strategies that “teach” the immune system to recognise and neutralise them, leading to safer, more effective cancer therapies.

My research develops a gentle cancer treatment using ultrasound to activate specialised LDH particles inside tumour cells. These particles release ROS “micro-explosions” that kill cancer without surgery or chemotherapy. Enhanced with MRI-visible metals, the method offers a safe, targeted therapy that destroys breast cancer cells using sound instead of pain.