Pain-sensing neurons require the gene PRDM12 not only to develop, but also to maintain their identity in adulthood. Removing PRDM12 causes neurons to express mixed identities, disrupting function. Understanding how neuron identity is preserved may enable regeneration of pain-sensing neurons and lead to new, non-addictive pain treatments.

This research investigates how children use the left and right hemispheres for language and spatial reasoning. Using ultrasound while children play custom games, it shows that those with the typical left-language/right-spatial pattern tend to have stronger skills. The findings reveal how brain-activity patterns relate to developmental risks and complex tasks like reading.

This research investigates genetic variants that influence how premature babies respond to infections and oxygen shortages—two major causes of brain injury. By analysing the DNA of over 200 premature infants, the study identifies variants linked to later movement and learning difficulties, aiming to enable earlier prediction, prevention, and personalised care.